EMC 2010 Initialization Failed

There is a time when my customer opens EMC 2010, an initialization failed eror appeared: The following error occurred while attempting to connect to the specified Exchange server.

After some research, I was hinted that this problem might related to proxy issue. You can read more here.

In order to verify the proxy settings, you can enter the command in CMD:

netsh winhttp show proxy

Once the result shows that there is a proxy server on the server, you can remove it by using command:

netsh winhttp reset proxy

And the problem resolved.